On a special day for the Mularkey family, Tully reflects on decades of work, love, grief and joy alongside her best friend. Kate faces the unknown.

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Tully, Johnny and Marah try to find ways of coping after Kate's revelation. In the 1980s, Johnny wrestles with another piece of overwhelming news.

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Kate and Johnny's loved ones gather for two very different celebrations. Tully gets tangled in a romantic dilemma, and Kate feels the weight of a secret.

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A bridal shower stirs up resentments and memories, an awkward encounter leads to a life-changing question, and a tragedy shakes teenage Kate's world.

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Johnny and Kate reminisce at a party about a life-changing kiss in the same newsroom, 20 years earlier. Tully gives Danny advice on his love life.

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From bra-stuffing to breastfeeding, Kate experiences several bumps in the road on her journey from a self-conscious teen to a first-time mother.

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Kate has often felt invisible next to Tully through the years. But amid major changes, Kate realizes she may need her best friend by her side.

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For the first time in decades, Kate and Tully experience a year apart — but can they handle major life events without each other?

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Kate learns that dealing with an ex is always tricky, no matter the decade. After years of never saying sorry, Tully struggles with accountability.

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Tully attempts to face unresolved loose ends from her past. But her choices lead to a potentially unforgivable mistake that impacts Kate's life.

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While celebrating their own freedom on Independence Day, Tully and Kate learn time and again that relying on each other may not be so bad after all.

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From a double date in 1975 to Tully's search for her father in 2004, Tully and Kate attempt to take charge of their futures — but fate has other plans.

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As Tully's career takes off, uncomfortable encounters at work keep throwing her off track. Johnny's behavior causes concern among his loved ones.

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A teen magazine. A political investigation. A secret message. Shocking revelations lead to major questions for Sean, Tully and Kate.

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Over the decades and several road trips, Tully and Kate strengthen their bond and forge new relationships while occasionally testing them.

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Trying times bring Kate and Tully together as they contend with an overbearing grandma, a pesky new intern and an ex-husband in distress.

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